Blar i forfatter "Kvaskoff, Marina"

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    • Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Karavasiloglou, Nena; Hüsing, Anika; Masala, Giovanna; van Gils, Carla H.; Fortner, Renée Turzanski; Chang-Claude, Jenny; Huybrechts, Inge; Weiderpass, Elisabete; Gunter, Marc; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Tjønneland, Anne; Kyrø, Cecilie; Dahm, Christina C.; Vistisen, Helene Tilma; Bakker, Marije F.; Sánchez, María-José; Chirlaque López, María Dolores; Santiuste, Carmen; Ardanaz, Eva; Menéndez, Virginia; Agudo, Antonio; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Peppa, Eleni; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Butt, Salma Tunå; Borgquist, Signe; Skeie, Guri; Schulze, Matthias; Key, Timothy; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Ellingjord-Dale, Merete; Riboli, Elio; Kaaks, Rudolf; Dossus, Laure; Rohrmann, Sabine; Kühn, Tilman (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-02)
      <i>Background</i> - Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, ...

    • Baseline and lifetime alcohol consumption and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Al-Rahmoun, Marie; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Lukic, Marko; Sánchez, Maria J.; Pala, Valeria; Tumino, Rosario; Chiodini, Paolo; Amiano, Pilar; Colorado-Yohar, Sandra; Chirlaque, María-Dolores; Ardanaz, Eva; Bonet, Catalina; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Overvad, Kim; Dahm, Christina C.; Antoniussen, Christian S.; Tjønneland, Anne; Kyrø, Cecilie; Bueno-de-Mesquita, Bas; Manjer, Jonas; Jansson, Malin; Esberg, Anders; Mori, Nagisa; Ferrari, Pietro; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Experimental evidence suggests that alcohol induces cutaneous carcinogenesis, yet epidemiological studies on the link between alcohol intake and skin cancer have been inconsistent. The European Prospective Investigation into Cancer and Nutrition (EPIC) is a prospective cohort initiated in 1992 in 10 European countries. Alcohol intake at baseline and average lifetime alcohol intake were assessed using ...

    • Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses 

      Dimou, Niki; Omiyale, Wemimo; Biessy, Carine; Viallon, Vivian; Kaaks, Rudolf; O'Mara, Tracy A.; Aglago, Elom K.; Ardanaz, Eva; Bergmann, Manuela M.; Bondonno, Nicola P.; Braaten, Tonje; Colorado-Yohar, Sandra M.; Crous-Bou, Marta; Dahm, Christina C.; Fortner, Renée T.; Gram, Inger Torhild; Harlid, Sophia; Heath, Alicia K.; Idahl, Annika; Kvaskoff, Marina; Nøst, Therese Haugdahl; Overvad, Kim; Palli, Domenico; Perez-Cornago, Aurora; Sacerdote, Carlotta; Sánchez, Maria-Jose; Schulze, Matthias B.; Severi, Gianluca; Simeon, Vittorio; Tagliabue, Giovanna; Tjønneland, Anne; Truong, Thérése; Tumino, Rosario; Johansson, Mattias; Weiderpass, Elisabete; Murphy, Neil; Gunter, Marc J.; Lacey, Ben; Allen, Naomi E.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-16)
      Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.<p> <p>Methods: The observational analyses included 286,415 ...

    • Circulating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort 

      Cairat, Manon; Rinaldi, Sabina; Navionis, Anne-Sophie; Romieu, Isabelle; Biessy, Carine; Viallon, Vivian; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Severi, Gianluca; Kvaskoff, Marina; Fortner, Renée T.; Kaaks, Rudolf; Aleksandrova, Krasimira; Schulze, Matthias B.; Masala, Giovanna; Tumino, Rosario; Sieri, Sabina; Grasso, Chiara; Mattiello, Amalia; Gram, Inger Torhild; Olsen, Karina Standahl; Agudo, Antonio; Etxezarreta, Pilar Amiano; Sánchez, Maria-Jose; Santiuste, Carmen; Barricarte, Aurelio; Monninkhof, Evelyn; Hiensch, Anouk E.; Muller, David; Merritt, Melissa A.; Travis, Ruth C.; Gunter, Marc J.; Dossus, Laure; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-18)
      Background: Infammation has been hypothesized to play a role in the development and progression of breast can‑ cer and might diferently impact breast cancer risk among pre and postmenopausal women. We performed a nested case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...

    • Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition 

      Bradbury, Kathryn E.; Appleby, Paul N.; Tipper, Sarah J.; Travis, Ruth C.; Allen, Naomi E.; Kvaskoff, Marina; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Cervenka, Iris; Mahamat-Saleh, Yahya; Bonnet, Fabrice; Kaaks, Rudolf; Fortner, Renée T.; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Stratigos, Alexander J.; Palli, Domenico; Grioni, Sara; Matullo, Giuseppe; Panico, Salvatore; Tumino, Rosario; Peeters, Petra H.; Bueno-de-Mesquita, H. Bas; Ghiasvand, Reza; Veierød, Marit B.; Weiderpass, Elisabete; Bonet, Catalina; Molina, Elena; Huerta, José M.; Larrañaga, Nerea; Barricarte, Aurelio; Merino, Susana; Isaksson, Karolin; Stocks, Tanja; Ljuslinder, Ingrid; Hemmingsson, Oskar; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Rinaldi, Sabina; Tsilidis, Konstantinos K.; Aune, Dagfinn; Riboli, Elio; Key, Timothy J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
      Insulin‐like growth factor‐I (IGF‐I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF‐I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF‐I concentrations ...

    • Circulating RANKL and RANKL/OPG and breast cancer risk by ER and PR subtype: Results from the EPIC cohort. 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Overvad, Kim; Holm, Marianne; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; His, Mathilde; Kvaskoff, Marina; Boeing, Heiner; Lagiou, Pagona; Papatesta, Eleni-Maria; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; van Gils, Carla H.; Peeters, Petra H.; Weiderpass, Elisabete; Agudo, Antonio; Sánchez, María-José; Chirlaque, Maria-Dolores; Ardanaz, Eva; Amiano, Pilar; Khaw, Kay Tee; Travis, Ruth; Dossus, Laure; Gunter, Mark; Rinaldi, Sabina; Merritt, Melissa; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-31)
      Receptor activator of nuclear factor-kappa B (RANK)-RANK ligand (RANKL) signaling promotes mammary tumor development in experimental models. Circulating concentrations of soluble RANKL (sRANKL) may influence breast cancer risk via activation of RANK signaling; this may be modulated by osteoprotegerin (OPG), the decoy receptor for RANKL. sRANKL and breast cancer risk by hormone receptor subtype has ...

    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...

    • Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Cervenka, Iris; Al-Rahmoun, Marie; Mancini, Francesca R.; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Trichopoulou, Antonia; Peppa, Eleni; La Vecchia, Carlo; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Perez-Cornago, Aurora; Jakszyn, Paula; Grioni, Sara; Schulze, Matthias B.; Skeie, Guri; Lasheras, Christina; Colorado-Yohar, Sandra; RodrÍguez-Barranco, Miguel; Kühn, Tilman; Katzke, Verena A.; Amiano, Pilar; Tumino, Rosario; Panico, Salvatore; Ezponda, Ana; Sonestedt, Emily; Scalbert, Augustin; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)
      Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers from ...

    • Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition 

      Caini, Saverio; Masala, Giovanna; Saieva, Calogero; Kvaskoff, Marina; Savoye, Isabelle; Sacerdote, Carlotta; Hemmingsson, Oskar; Hammer Bech, Bodil; Overvad, Kim; Tjønneland, Anne; Petersen, Kristina E.N.; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Cervenka, Iris; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Floegel, Anna; Trichopoulou, Antonia; Valanou, Elisavet; Kritikou, Maria; Tagliabue, Giovanna; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Veierød, Marit Bragelien; Ghiasvand, Reza; Lukic, Marko; Quirós, José Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Salamanca Fernández, Elena; Larrañaga, Nerea; Zamora-Ros, Raul; Maria Nilsson, Lena; Ljuslinder, Ingrid; Jirström, Karin; Sonestedt, Emily; Key, Timothy J.; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Huybrechts, Inge; Murphy, Neil; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Palli, Domenico (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-20)
      In vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma; however, epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC ...

    • Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort 

      Fortner, Renée T.; Vitonis, Allison F.; Schock, Helena; Hüsing, Anika; Johnson, Theron; Fichorova, Raina Nakove; Fashemi, Titilayo; Yamamoto, Hidemi S.; Tjønneland, Anne; Hansen, Louise; Overvad, Kim; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Severi, Gianluca; Boeing, Heiner; Trichopoulou, Antonia; Benetou, Vassiliki; La Vecchia, Carlo; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Matullo, Giuseppe; Mattiello, Amalia; Onland-Moret, N. Charlotte; Peeters, Petra H.; Weiderpass, Elisabete; Gram, Inger Torhild; Jareid, Mie; Quirós, José Ramón; Duell, Eric J.; Sánchez, Mariá-José; Chirlaque, María-Dolores; Ardanaz, Eva; Larrañaga, Nerea; Nodin, Björn; Brändstedt, Jenny; Idahl, Annika; Khaw, Kay-Tee; Allen, Naomi; Gunter, Marc; Johansson, Mattias; Dossus, Laure; Merritt, Melissa A.; Riboli, Elio; Cramer, Daniel W.; Kaaks, Rudolf; Terry, Kathryn L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-20)
      Background: Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. <br>Methods: We evaluated cross-sectional relationships between lifestyle and reproductive factors and these markers among controls ( n = 1910) from a nested case-control study in the European Prospective Investigation into Cancer and Nutrition ...

    • Development and validation of circulating CA125 prediction models in postmenopausal women 

      Sasamoto, Naoko; Babic, Ana; Rosner, Bernard A.; Fortner, Renée T.; Vitonis, Allison F; Yamamoto, Hidemi; Fichorova, Raina N.; Titus, Linda J.; Tjønneland, Anne; Hansen, Louise; Kvaskoff, Marina; Fournier, Agnès; Mancini, Francesca Romana; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Mattiello, Amalia; Tumino, Rosario; Fiano, Valentina; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Gram, Inger Torhild; Quirós, José Ramón; Lujan-Barroso, Leila; Sánchez, María-José; Colorado-Yohar, Sandra; Barricarte, Aurelio; Amiano, Pilar; Idahl, Annika; Lundin, Eva; Sartor, Hanna; Khaw, Kay-Tee; Key, Timothy J.; Muller, David; Riboli, Elio; Gunter, Marc; Dossus, Laure; Trabert, Britton; Wentzensen, Nicolas; Kaaks, Rudolf; Cramer, Daniel W.; Tworoger, Shelley S.; Terry, Kathryn L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-26)
      <i>Background</i> - Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to improve its performance as screening biomarker.<p><p> <i>Methods</i> - We developed and validated ...

    • Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and breast cancer risk in 9 European countries 

      Fiolet, Thibault; Casagrande, Corinne; Nicolas, Geneviève; Horvath, Zsuzsanna; Frenoy, Pauline; Weiderpass, Elisabete; Katzke, Verena; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Panico, Salvatore; Sacerdote, Carlotta; Manjer, Jonas; Sonestedt, Emily; Grioni, Sara; Agudo, Antonio; Rylander, Charlotta; Nøst, Therese Haugdahl; Skeie, Guri; Tjønneland, Anne; Raaschou-Nielsen, Ole; Ardanaz, Eva; Amiano, Pilar; Dolores Chirlaque López, María; Schulze, Matthias B.; Wennberg, Maria; Harlid, Sophia; Cairat, Manon; Kvaskoff, Marina; Huybrechts, Inge; Romana Mancini, Francesca (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-26)
      Background: Dioxins and polychlorobiphenyls (PCBs) are persistent organic pollutants that have demonstrated endocrine disrupting properties. Several of these chemicals are carcinogenic and positive associations have been suggested with breast cancer risk. In general population, diet represents the main source of exposure.<p><p> Methods: Associations between dietary intake of 17 dioxins and 35 PCBs ...

    • Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: a Prospective Study and Meta-Analysis 

      Mori, Nagisa; Keski-Rahkonen, Pekka; Gicquiau, Audrey; Rinaldi, Sabina; Dimou, Niki; Harlid, Sophia; Harbs, Justin; Van Guelpen, Bethany; Aune, Dagfinn; Cross, Amanda J.; Tsilidis, Konstantinos K.; Severi, Gianluca; Kvaskoff, Marina; Fournier, Agnès; Kaaks, Rudolf; Fortner, Renée Turzanski; Schulze, Matthias B.; Jakszyn, Paula; Sánchez, Maria-José; Colorado-Yohar, Sandra M.; Ardanaz, Eva; Travis, Ruth; Watts, Eleanor L.; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Buenode-Mesquita, bas; Gram, Inger Torhild; Waaseth, Marit; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Background - Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk, but epidemiologic studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.<p> <p>Methods - We investigated the associations between circulating concentrations ...

    • Exogenous hormone use and cutaneous melanoma risk in women: The European Prospective Investigation into Cancer and Nutrition 

      Cervenka, Iris; Al Rahmoun, Marie; Mahamat-Saleh, Yahya; Fournier, Agnès; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Caini, Saverio; Palli, Domenico; Ghiasvand, Reza; Veierød, Marit Bragelien; Botteri, Edoardo; Tjønneland, Anne; Olsen, Anja; Fortner, Renée T.; Kaaks, Rudolf; Schulze, Matthias B.; Panico, Salvatore; Trichopoulou, Antonia; Dessinioti, Clio; Niforou, Katerina; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastiaan; Sandanger, Torkjel M; Colorado-Yohar, Sandra; Sánchez, María-José; Gil Majuelo, Leire; Lujan-Barroso, Leila; Ardanaz, Eva; Merino, Susana; Isaksson, Karolin; Butt, Salma; Ljuslinder, Ingrid; Jansson, Malin; Travis, Ruth C.; Khaw, Kay-Tee; Weiderpass, Elisabete; Dossus, Laure; Rinaldi, Sabina; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 10 ...

    • Fruit and vegetable consumption in relation to hepatocellular carcinoma in a multi-centre, European cohort study 

      Bamia, Christina; Lagiou, Pagona; Jenab, Mazda; Aleksandrova, Krasimira; Fedirko, Veronika; Trichopoulos, Dimitrios; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Katzke, Verena A.; Kühn, Tilman; Boeing, Heiner; Nöthlings, Ute; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosaria; Naccarati, Allessio; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.M.; Weiderpass, Elisabete; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Chirlaque, María-Dolores; Sánchez, María-José; Ardanaz, Eva; Dorronsoro, Miren; Ericson, Ulrika; Nilsson, Lena Maria; Wennberg, Maria; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Stepien, Magdalena; Duarte-Salles, Talita; Norat, Teresa; Murphy, Neil; Riboli, Eilo; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-05)
      Background: Vegetable and/or fruit intakes in association with hepatocellular carcinoma (HCC) risk have been investigated in case–control studies conducted in specific European countries and cohort studies conducted in Asia, with inconclusive results. No multi-centre European cohort has investigated the indicated associations. Methods: In 486 799 men/women from the European Prospective Investigation ...

    • Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: A multinational cohort study 

      Murphy, Neil; Ward, Heather A.; Jenab, Mazda; Rothwell, Joseph A.; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Dahm, Christina C.; Jakszyn, Paula; Sánchez, María-José; Gil, Leire; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Trichopoulou, Antonia; La Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; Gylling, Björn; Myte, Robin; Jirström, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda J.; Gunter, Mark J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      <i>Background & Aims</i> - Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision.<p><p> <i>Methods</i> - In the European Prospective Investigation ...

    • High levels of C-reactive protein are associated with an increased risk of ovarian cancer: Results from the Ovarian Cancer Cohort Consortium 

      Peres, Lauren C.; Mallen, Adrianne R.; Townsend, Mary K.; Poole, Elizabeth M.; Trabert, Britton; Allen, Naomi E.; Arslan, Alan A.; Dossus, Laure; Fortner, Renee T.; Gram, Inger T.; Hartge, Patricia; Idahl, Annika; Kaaks, Rudolf; Kvaskoff, Marina; Magliocco, Anthony M.; Merritt, Melissa A.; Quirós, Ramón; Tjonneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; van Gils, Carla H.; Visvanathan, Kala; Wentzensen, Nicolas; Zeleniuch-Jacquotte, Anne; Tworoger, Shelley S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-28)
      Growing epidemiologic evidence supports chronic inflammation as a mechanism of ovarian carcinogenesis. An association between a circulating marker of inflammation, C-reactive protein (CRP), and ovarian cancer risk has been consistently observed, yet, potential heterogeneity of this association by tumor and patient characteristics has not been adequately explored. In this study, we pooled data from ...

    • Menstrual factors, reproductive history, hormone use, and urothelial carcinoma risk: A prospective study in the EPIC cohort 

      Lujan-Barroso, Leila; Botteri, Edoardo; Caini, Saverio; Ljungberg, Börje; Roswall, Nina; Tjønneland, Anne; Bueno-De-Mesquita, Bas; Gram, Inger Torhild; Tumino, Rosario; Kiemeney, Lambertus A.; Liedberg, Fredrik; Stocks, Tanja; Gunter, Marc; Murphy, Neil; Cervenka, Iris; Fournier, Agnès; Kvaskoff, Marina; Häggström, Christel; Overvad, Kim; Lund, Eiliv; Waaseth, Marit; Fortner, Renée T.; Kühn, Tilman; Menéndez, Virginia; Sánchez, María-José; Santiuste, Carmen; Perez-Cornago, Aurora; Zamora-Ros, Raul; Cross, Amanda J.; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Krogh, Vittorio; Sciannameo, Veronica; Mattiello, Amalia; Panico, Salvatore; van Gils, Carla H.; Onland-Moret, N. Charlotte; Barricarte, Aurelio; Amiano, Pilar; Khaw, Kay-Tee; Boeing, Heiner; Weiderpass, Elisabete; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-28)
      <p>Background: Urothelial carcinoma is the predominant (95%) bladder cancer subtype in industrialized nations. Animal and epidemiologic human studies suggest that hormonal factors may influence urothelial carcinoma risk. <p>Methods: We used an analytic cohort of 333,919 women from the European Prospective Investigation into Cancer and Nutrition Cohort. Associations between hormonal factors and ...

    • Polyphenol Intake and Epithelial Ovarian Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study 

      Londono, Catalina; Cayssials, Valerie; de Villasante, Izar; Crous-Bou, Marta; Scalbert, Augustin; Weiderpass, Elisabete; Agudo, Antonio; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Katzke, Verena; Schulze, Matthias; Palli, Domenico; Krogh, Vittorio; De Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Gram, Inger Torhild; Rylander, Charlotta; Skeie, Guri; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Sartor, Hanna; Sonestedt, Emily; Esberg, Anders; Idahl, Annika; Mahamat-Saleh, Yahya; Laouali, Nasser; Kvaskoff, Marina; Turzanski-Fortner, Renée; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-04)
      Despite some epidemiological evidence on the protective effects of polyphenol intake on epithelial ovarian cancer (EOC) risk from case-control studies, the evidence is scarce from prospective studies and non-existent for several polyphenol classes. Therefore, we aimed to investigate the associations between the intake of total, classes and subclasses of polyphenols and EOC risk in a large ...

    • Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Chang-Claude, Jenny; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Karakatsani, Anna; Trichopoulou, Antonia; La Vecchia, Carlo; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; van Gils, Carla H.; Peeters, Petra H.M.; Weiderpass, Elisabete; Agudo, Antonio; Rodríguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Gil, Leire; Kaw, Kay Tee; Schmidt, Julie A.; Dossus, Laure; His, Mathilde; Aune, Dagfinn; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Peer reviewed, 2018-10-22)
      <b>Background</b><br> Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble RANKL (sRANKL) and OPG are associated with breast cancer risk. Here we extend these findings to ...